BAIT
SLC12A2
BSC, BSC2, NKCC1, PPP1R141
solute carrier family 12 (sodium/potassium/chloride transporter), member 2
GO Process (8)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SLC12A2
BSC, BSC2, NKCC1, PPP1R141
solute carrier family 12 (sodium/potassium/chloride transporter), member 2
GO Process (8)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-purification
An interaction is inferred from the identification of two or more protein subunits in a purified protein complex, as obtained by classical biochemical fractionation or affinity purification and one or more additional fractionation steps.
Publication
The structural unit of the secretory Na+-K+-2Cl- cotransporter (NKCC1) is a homodimer.
The oligomeric state of the secretory Na(+)-K(+)-2Cl(-) cotransporter (NKCC1) in rat parotid plasma membranes was studied using the reversible chemical cross-linker DTSSP [3, 3'-dithiobis(sulfosuccinimidyl propionate)]. The monomeric apparent molecular mass of NKCC1 is approximately 170 kDa. However, we show here that this protein migrates as a approximately 355 kDa complex on SDS-PAGE gels after membrane treatment with DTSSP, indicating that ... [more]
Biochemistry Apr. 04, 2000; 39(13);3718-24 [Pubmed: 10736171]
Throughput
- Low Throughput
Curated By
- BioGRID