SNAP25
Gene Ontology Biological Process
- axonogenesis [IEP]
- calcium ion-dependent exocytosis of neurotransmitter [IDA]
- endosomal transport [IDA]
- exocytosis [TAS]
- growth hormone secretion [IEP]
- long-term memory [IMP]
- long-term synaptic potentiation [ISO]
- neurotransmitter secretion [ISO]
- positive regulation of hormone secretion [IMP]
- positive regulation of insulin secretion [IEP]
- potassium ion transmembrane transport [IDA]
- regulation of establishment of protein localization [ISO]
- regulation of neuron projection development [IMP]
- regulation of synapse assembly [IEP]
- sleep [IDA]
- synaptic vesicle fusion to presynaptic membrane [IBA]
- synaptic vesicle priming [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- BLOC-1 complex [ISO, ISS]
- SNARE complex [IDA, ISO]
- actin cytoskeleton [IDA]
- axon [IDA]
- axonal growth cone [IDA]
- cell [ISO]
- cytoplasm [IDA, ISO]
- cytosol [IDA]
- endosome [IDA]
- filopodium [IDA]
- growth cone [IDA]
- intracellular organelle [IDA]
- lamellipodium [IDA]
- membrane [ISO, ISS]
- membrane raft [IDA]
- myelin sheath [ISO]
- neuron projection [IDA]
- neuronal cell body [IDA]
- perinuclear region of cytoplasm [ISO]
- plasma membrane [IDA]
- synapse [ISO]
- synaptobrevin 2-SNAP-25-syntaxin-1a complex [IDA]
- synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex [IDA, ISO]
- synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex [IDA]
- terminal bouton [IDA]
- trans-Golgi network [ISO]
- vesicle [ISO]
- voltage-gated potassium channel complex [IDA]
STX3
Gene Ontology Biological Process
- intracellular protein transport [IBA]
- neuron projection development [ISS]
- positive regulation of cell adhesion [IMP]
- positive regulation of cell proliferation [IMP]
- positive regulation of chemotaxis [IMP]
- positive regulation of protein localization to cell surface [IMP]
- positive regulation of protein localization to plasma membrane [IMP]
- synaptic vesicle fusion to presynaptic membrane [IBA]
- vesicle docking [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- SNARE complex [IBA, ISS]
- apical plasma membrane [IDA]
- azurophil granule [IDA]
- cell-cell junction [IDA]
- extracellular vesicular exosome [IDA]
- growth cone [ISS]
- integral component of membrane [IBA]
- lamellipodium [IDA]
- neuron projection [ISS]
- plasma membrane [IDA]
- specific granule [IDA]
- synaptic vesicle [IBA]
- vacuole [TAS]
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Inhibition of the binding of SNAP-23 to syntaxin 4 by Munc18c.
SNARE proteins have been implicated in the insulin-induced translocation of vesicles containing the GLUT4 glucose transporter to the plasma membrane of adipocytes. The role of the target SNARE SNAP-25 or its homologs in this process was investigated by screening a mouse adipocyte cDNA library with rat SNAP-25 and human SNAP-23 cDNA probes. Both positive clones isolated encoded a protein with ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| STX3 SNAP25 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | Low | - | BioGRID | - |
Curated By
- BioGRID