BAIT
STXBP1
MUNC18-1, NSEC1, P67, RBSEC1, UNC18, RP11-56D16.3
syntaxin binding protein 1
GO Process (15)
GO Function (5)
GO Component (8)
Gene Ontology Biological Process
- axon target recognition [ISS]
- energy reserve metabolic process [TAS]
- glutamate secretion [TAS]
- negative regulation of synaptic transmission, GABAergic [ISS]
- neurotransmitter secretion [TAS]
- platelet aggregation [IMP]
- platelet degranulation [IMP]
- protein localization to plasma membrane [IDA]
- regulation of SNARE complex assembly [TAS]
- regulation of insulin secretion [TAS]
- regulation of synaptic vesicle fusion to presynaptic membrane [TAS]
- regulation of synaptic vesicle priming [ISS]
- small molecule metabolic process [TAS]
- synaptic transmission [TAS]
- synaptic vesicle maturation [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
APBA1
Mint1
amyloid beta (A4) precursor protein-binding, family A, member 1
GO Process (9)
GO Function (5)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Mints, Munc18-interacting proteins in synaptic vesicle exocytosis.
Munc18-1 is a neuronal protein that interacts with syntaxin 1 and is required for synaptic vesicle exocytosis. We have now identified two Munc18-1-interacting proteins called Mint1 and Mint2 that may mediate the function of Munc18-1. Mint proteins are detectable only in brain and are composed of an N-terminal sequence that binds Munc18-1, a middle phosphotyrosine-binding domain, and two C-terminal PDZ ... [more]
J. Biol. Chem. Dec. 12, 1997; 272(50);31459-64 [Pubmed: 9395480]
Throughput
- Low Throughput
Curated By
- BioGRID