BAIT
COL14A1
UND
collagen, type XIV, alpha 1
GO Process (5)
GO Function (4)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
CD44
CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1, AL133330.1
CD44 molecule (Indian blood group)
GO Process (25)
GO Function (5)
GO Component (8)
Gene Ontology Biological Process
- blood coagulation [TAS]
- carbohydrate metabolic process [TAS]
- cartilage development [IEP]
- cell-matrix adhesion [NAS]
- cellular response to fibroblast growth factor stimulus [IDA]
- cytokine-mediated signaling pathway [TAS]
- extracellular matrix disassembly [TAS]
- extracellular matrix organization [TAS]
- glycosaminoglycan metabolic process [TAS]
- hyaluronan catabolic process [IDA, TAS]
- hyaluronan metabolic process [TAS]
- interferon-gamma-mediated signaling pathway [TAS]
- leukocyte migration [TAS]
- monocyte aggregation [IMP]
- negative regulation of DNA damage response, signal transduction by p53 class mediator [IDA]
- negative regulation of apoptotic process [IMP]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [IMP]
- negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [IDA]
- positive regulation of ERK1 and ERK2 cascade [IDA]
- positive regulation of heterotypic cell-cell adhesion [IMP]
- positive regulation of monocyte aggregation [IMP]
- positive regulation of peptidyl-serine phosphorylation [IDA]
- positive regulation of peptidyl-tyrosine phosphorylation [IDA]
- single organismal cell-cell adhesion [NAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-purification
An interaction is inferred from the identification of two or more protein subunits in a purified protein complex, as obtained by classical biochemical fractionation or affinity purification and one or more additional fractionation steps.
Publication
A chondroitin/dermatan sulfate form of CD44 is a receptor for collagen XIV (undulin).
Collagen XIV, a fibril-associated collagen with interrupted triple helices, is expressed in differentiated soft connective tissues and in cartilage. However, a cellular receptor for this protein has not been identified. Here we show that human placental collagen XIV, isolated by a mild and simple two-step method, serves as adhesive protein for a variety of mesenchymal and some epithelial cells. Cell ... [more]
Exp. Cell Res. Dec. 15, 1996; 229(2);388-97 [Pubmed: 8986622]
Throughput
- Low Throughput
Curated By
- BioGRID