BAIT
DPYSL2
AI851130, Crmp2, DRP2, Musunc33, TOAD-64, Ulip2
dihydropyrimidinase-like 2
GO Process (6)
GO Function (2)
GO Component (13)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
FZD2
AL033370, AW456835, Fz10, Fzd10, Mfz10, Mfz10a, RP23-57F11.2
frizzled homolog 2 (Drosophila)
GO Process (20)
GO Function (7)
GO Component (5)
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [IBA]
- G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger [ISO]
- Wnt signaling pathway, calcium modulating pathway [ISO]
- canonical Wnt signaling pathway [IBA, ISO]
- cell-cell signaling [IDA]
- cochlea morphogenesis [IGI]
- epithelial cell differentiation [IDA, IGI]
- hard palate development [IGI, IMP]
- inner ear receptor cell development [IGI]
- membranous septum morphogenesis [IGI]
- muscular septum morphogenesis [IGI]
- outflow tract morphogenesis [IGI]
- planar cell polarity pathway involved in neural tube closure [IGI]
- positive regulation of cGMP metabolic process [ISO]
- positive regulation of cytosolic calcium ion concentration [ISO]
- positive regulation of sequence-specific DNA binding transcription factor activity [ISO]
- positive regulation of transcription, DNA-templated [ISO]
- sensory perception of smell [IMP]
- signal transduction [IDA]
- ventricular septum morphogenesis [IGI]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The protein interactome of collapsin response mediator protein-2 (CRMP2/DPYSL2) reveals novel partner proteins in brain tissue.
Collapsin response mediator protein-2 (CRMP2) is a CNS protein involved in neuronal development, axonal and neuronal growth, cell migration, and protein trafficking. Recent studies have linked perturbations in CRMP2 function to neurodegenerative disorders such as Alzheimer's disease, neuropathic pain, and Batten disease, and to psychiatric disorders such as schizophrenia. Like most proteins, CRMP2 functions though interactions with a molecular network ... [more]
Proteomics Clin Appl Oct. 01, 2015; 9(9-10);817-31 [Pubmed: 25921334]
Throughput
- High Throughput
Curated By
- BioGRID