BAIT
DPYSL2
AI851130, Crmp2, DRP2, Musunc33, TOAD-64, Ulip2
dihydropyrimidinase-like 2
GO Process (6)
GO Function (2)
GO Component (13)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
ROCK2
B230113H15Rik, ROKalpha, Rho-kinase, Rock-II, Rock2m, mKIAA0619
Rho-associated coiled-coil containing protein kinase 2
GO Process (11)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- Rho protein signal transduction [ISO]
- actin cytoskeleton organization [IGI]
- centrosome duplication [ISO]
- dendrite morphogenesis [IGI]
- extrinsic apoptotic signaling pathway via death domain receptors [IGI]
- negative regulation of angiogenesis [ISO]
- neural tube closure [IGI]
- positive regulation of centrosome duplication [IMP]
- protein phosphorylation [ISO]
- regulation of circadian rhythm [IMP]
- regulation of keratinocyte differentiation [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The protein interactome of collapsin response mediator protein-2 (CRMP2/DPYSL2) reveals novel partner proteins in brain tissue.
Collapsin response mediator protein-2 (CRMP2) is a CNS protein involved in neuronal development, axonal and neuronal growth, cell migration, and protein trafficking. Recent studies have linked perturbations in CRMP2 function to neurodegenerative disorders such as Alzheimer's disease, neuropathic pain, and Batten disease, and to psychiatric disorders such as schizophrenia. Like most proteins, CRMP2 functions though interactions with a molecular network ... [more]
Proteomics Clin Appl Oct. 01, 2015; 9(9-10);817-31 [Pubmed: 25921334]
Throughput
- High Throughput
Curated By
- BioGRID