BAIT
DPYSL2
AI851130, Crmp2, DRP2, Musunc33, TOAD-64, Ulip2
dihydropyrimidinase-like 2
GO Process (6)
GO Function (2)
GO Component (13)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
RPS3
D7Ertd795e, Rs_3
ribosomal protein S3
GO Process (7)
GO Function (11)
GO Component (12)
Gene Ontology Biological Process
- DNA catabolic process, endonucleolytic [IBA, ISO]
- DNA repair [IBA]
- cytoplasmic translation [IBA]
- negative regulation of DNA repair [ISO]
- positive regulation of DNA N-glycosylase activity [ISO]
- positive regulation of NF-kappaB transcription factor activity [ISO]
- positive regulation of apoptotic signaling pathway [ISO]
Gene Ontology Molecular Function- DNA-(apurinic or apyrimidinic site) lyase activity [ISO]
- NF-kappaB binding [ISO]
- damaged DNA binding [IBA, ISO]
- enzyme binding [ISO]
- mRNA binding [ISO]
- oxidized purine nucleobase lesion DNA N-glycosylase activity [IBA]
- poly(A) RNA binding [ISO]
- protein binding [IPI]
- protein kinase A binding [ISO]
- protein kinase binding [ISO]
- structural constituent of ribosome [IBA, ISO]
- DNA-(apurinic or apyrimidinic site) lyase activity [ISO]
- NF-kappaB binding [ISO]
- damaged DNA binding [IBA, ISO]
- enzyme binding [ISO]
- mRNA binding [ISO]
- oxidized purine nucleobase lesion DNA N-glycosylase activity [IBA]
- poly(A) RNA binding [ISO]
- protein binding [IPI]
- protein kinase A binding [ISO]
- protein kinase binding [ISO]
- structural constituent of ribosome [IBA, ISO]
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The protein interactome of collapsin response mediator protein-2 (CRMP2/DPYSL2) reveals novel partner proteins in brain tissue.
Collapsin response mediator protein-2 (CRMP2) is a CNS protein involved in neuronal development, axonal and neuronal growth, cell migration, and protein trafficking. Recent studies have linked perturbations in CRMP2 function to neurodegenerative disorders such as Alzheimer's disease, neuropathic pain, and Batten disease, and to psychiatric disorders such as schizophrenia. Like most proteins, CRMP2 functions though interactions with a molecular network ... [more]
Proteomics Clin Appl Oct. 01, 2015; 9(9-10);817-31 [Pubmed: 25921334]
Throughput
- High Throughput
Curated By
- BioGRID