BAIT
PPOX
PPO, V290M, VP
protoporphyrinogen oxidase
GO Process (5)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SLC25A4
AU019225, Ant1
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
GO Process (9)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
- apoptotic mitochondrial changes [IGI]
- ion transmembrane transport [ISO]
- negative regulation of cardiac muscle cell apoptotic process [ISO]
- negative regulation of mitochondrial membrane permeability involved in apoptotic process [ISO]
- negative regulation of necroptotic process [ISO]
- nucleotide transmembrane transport [ISO]
- positive regulation of cell growth involved in cardiac muscle cell development [ISO]
- positive regulation of oxidative phosphorylation uncoupler activity [ISO]
- purine nucleoside transmembrane transport [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification of the Mitochondrial Heme Metabolism Complex.
Heme is an essential cofactor for most organisms and all metazoans. While the individual enzymes involved in synthesis and utilization of heme are fairly well known, less is known about the intracellular trafficking of porphyrins and heme, or regulation of heme biosynthesis via protein complexes. To better understand this process we have undertaken a study of macromolecular assemblies associated with ... [more]
PLoS ONE Aug. 20, 2015; 10(8);e0135896 [Pubmed: 26287972]
Throughput
- High Throughput
Curated By
- BioGRID