BAIT
C3
AHUS5, ARMD9, ASP, C3a, C3b, CPAMD1, HEL-S-62p
complement component 3
GO Process (15)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [TAS]
- complement activation [IMP, TAS]
- complement activation, alternative pathway [TAS]
- immune response [TAS]
- innate immune response [TAS]
- positive regulation of G-protein coupled receptor protein signaling pathway [IDA]
- positive regulation of apoptotic cell clearance [IMP]
- positive regulation of glucose transport [IDA]
- positive regulation of lipid storage [IDA]
- positive regulation of protein phosphorylation [IDA]
- positive regulation vascular endothelial growth factor production [IDA]
- regulation of complement activation [TAS]
- regulation of immune response [TAS]
- regulation of triglyceride biosynthetic process [IDA]
- signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
CFP
BFD, PFC, PFD, PROPERDIN
complement factor properdin
GO Process (6)
GO Function (0)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Analysis of the interactions between properdin, the third component of complement (C3), and its physiological activation products.
The interactions of properdin with both surface-bound and fluid-phase C3 (the third component of complement) and its activation products have been investigated by using a purified preparation of the 'native' form. At physiological ionic strength, a weak interaction with cell-bound C3b (the larger activation fragment of C3) could be demonstrated. In the presence of Factor B this interaction was enhanced, ... [more]
Biochem. J. May. 15, 1988; 252(1);47-54 [Pubmed: 3421908]
Throughput
- Low Throughput
Related interactions
Curated By
- BioGRID