BAIT
ZPR1
AI303781, Zfp259, Znf259
ZPR1 zinc finger
GO Process (17)
GO Function (4)
GO Component (11)
Gene Ontology Biological Process
- Cajal body organization [IMP, ISO]
- DNA endoreduplication [IMP]
- apoptotic process involved in development [IMP]
- axon development [IMP, ISO]
- cellular response to epidermal growth factor stimulus [ISO]
- inner cell mass cell proliferation [IMP]
- microtubule cytoskeleton organization [IMP]
- negative regulation of motor neuron apoptotic process [IMP]
- positive regulation of RNA splicing [ISO]
- positive regulation of gene expression [IMP, ISO]
- positive regulation of growth [IMP]
- positive regulation of protein import into nucleus [IMP, ISO]
- positive regulation of transcription involved in G1/S transition of mitotic cell cycle [ISO]
- pre-mRNA catabolic process [ISO]
- regulation of myelination [IMP]
- spinal cord development [IMP]
- trophectodermal cell proliferation [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
EEF1A1
CCS-3, CCS3, EE1A1, EEF-1, EEF1A, EF-Tu, EF1A, GRAF-1EF, HNGC:16303, LENG7, PTI1, eEF1A-1, RP11-505P4.2
eukaryotic translation elongation factor 1 alpha 1
GO Process (5)
GO Function (5)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Interaction of ZPR1 with translation elongation factor-1alpha in proliferating cells.
The zinc finger protein ZPR1 is present in the cytoplasm of quiescent mammalian cells and translocates to the nucleus upon treatment with mitogens, including epidermal growth factor (EGF). Homologues of ZPR1 were identified in yeast and mammals. These ZPR1 proteins bind to eukaryotic translation elongation factor-1alpha (eEF-1alpha). Studies of mammalian cells demonstrated that EGF treatment induces the interaction of ZPR1 ... [more]
J. Cell Biol. Dec. 14, 1998; 143(6);1471-84 [Pubmed: 9852145]
Throughput
- Low Throughput
Curated By
- BioGRID