EEF1A1
Gene Ontology Biological Process
Gene Ontology Molecular Function
ZPR1
Gene Ontology Biological Process
- Cajal body organization [IMP, ISS]
- DNA endoreduplication [ISS]
- apoptotic process involved in development [ISS]
- axon development [IMP, ISS]
- cell proliferation [TAS]
- cellular response to epidermal growth factor stimulus [IDA]
- microtubule cytoskeleton organization [ISS]
- negative regulation of motor neuron apoptotic process [ISS]
- positive regulation of RNA splicing [IMP]
- positive regulation of gene expression [IMP]
- positive regulation of growth [ISS]
- positive regulation of protein import into nucleus [IDA]
- positive regulation of transcription involved in G1/S transition of mitotic cell cycle [IMP]
- pre-mRNA catabolic process [IMP]
- regulation of myelination [ISS]
- signal transduction [TAS]
- spinal cord development [ISS]
- trophectodermal cell proliferation [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Interaction of ZPR1 with translation elongation factor-1alpha in proliferating cells.
The zinc finger protein ZPR1 is present in the cytoplasm of quiescent mammalian cells and translocates to the nucleus upon treatment with mitogens, including epidermal growth factor (EGF). Homologues of ZPR1 were identified in yeast and mammals. These ZPR1 proteins bind to eukaryotic translation elongation factor-1alpha (eEF-1alpha). Studies of mammalian cells demonstrated that EGF treatment induces the interaction of ZPR1 ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| EEF1A1 ZPR1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.8853 | BioGRID | 2260544 | |
| ZPR1 EEF1A1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.8198 | BioGRID | 3271210 | |
| EEF1A1 ZPR1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9589 | BioGRID | 3068506 | |
| ZPR1 EEF1A1 | Co-fractionation Co-fractionation Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex. | High | 0.1656 | BioGRID | 1261362 |
Curated By
- BioGRID