Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

Neurite outgrowth by the alternatively spliced region of human tenascin-C is mediated by neuronal alpha7beta1 integrin.

Mercado ML, Nur-e-Kamal A, Liu HY, Gross SR, Movahed R, Meiners S

The region of tenascin-C containing only alternately spliced fibronectin type-III repeat D (fnD) increases neurite outgrowth by itself and also as part of tenascin-C. We previously localized the active site within fnD to an eight amino acid sequence unique to tenascin-C, VFDNFVLK, and showed that the amino acids FD and FV are required for activity. The purpose of this study ... [more]

J. Neurosci. Jan. 07, 2004; 24(1);238-47 [Pubmed: 14715956]

Throughput

  • Low Throughput

Curated By

  • BioGRID