EHD1
Gene Ontology Biological Process
- blood coagulation [TAS]
- cellular response to nerve growth factor stimulus [ISS]
- cholesterol homeostasis [ISS]
- endocytic recycling [IGI, IMP]
- endocytosis [IMP]
- intracellular protein transport [IMP]
- low-density lipoprotein particle clearance [ISS]
- neuron projection development [ISS]
- positive regulation of cholesterol storage [ISS]
- positive regulation of endocytic recycling [ISS]
- positive regulation of myoblast fusion [ISS]
- protein homooligomerization [IPI]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
SNAP29
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Association of insulin-like growth factor 1 receptor with EHD1 and SNAP29.
Ligand-induced receptor-mediated endocytosis plays a central role in regulating signaling conveyed by tyrosine kinase receptors. This process depends on the recruitment of the adaptor protein 2 (AP-2) complex, clathrin, dynamin, and other accessory proteins to the ligand-bound receptor. We show here that besides AP-2 and clathrin, two other proteins participate in the endocytic process of the insulin-like growth factor receptor ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| SNAP29 EHD1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9991 | BioGRID | 3174991 | |
| SNAP29 EHD1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | Low | - | BioGRID | - | |
| SNAP29 EHD1 | Reconstituted Complex Reconstituted Complex An interaction is detected between purified proteins in vitro. | Low | - | BioGRID | - | |
| EHD1 SNAP29 | Reconstituted Complex Reconstituted Complex An interaction is detected between purified proteins in vitro. | Low | - | BioGRID | - | |
| SNAP29 EHD1 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | 2704576 |
Curated By
- BioGRID