BAIT
CHRNE
ACHRE, CMS1D, CMS1E, CMS2A, FCCMS, SCCMS
cholinergic receptor, nicotinic, epsilon (muscle)
GO Process (7)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
CHRNA1
ACHRA, ACHRD, CHRNA, CMS2A, FCCMS, SCCMS
cholinergic receptor, nicotinic, alpha 1 (muscle)
GO Process (15)
GO Function (4)
GO Component (5)
Gene Ontology Biological Process
- cation transmembrane transport [IMP, ISS, TAS]
- ion transmembrane transport [TAS]
- muscle cell cellular homeostasis [IMP]
- musculoskeletal movement [IMP]
- neuromuscular junction development [IMP]
- neuromuscular process [IMP]
- neuromuscular synaptic transmission [IMP]
- neuron cellular homeostasis [IMP]
- neuronal action potential [IMP]
- regulation of membrane potential [IMP]
- signal transduction [TAS]
- skeletal muscle contraction [IMP]
- skeletal muscle tissue growth [IMP]
- synaptic transmission [TAS]
- transport [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Extracellular domains mediating epsilon subunit interactions of muscle acetylcholine receptor.
Ligand-gated ion channels, a major class of cell-surface proteins, have a pseudosymmetric structure with five highly homologous subunits arranged around a central ion pore. The correct assembly of each channel, whose subunit composition varies with cell type and stage of development, requires specific recognition between the subunits. Assembly of the pentameric form of the acetylcholine receptor from adult muscle (AChR; ... [more]
Nature Jul. 04, 1991; 352(6330);64-7 [Pubmed: 1712080]
Throughput
- Low Throughput
Curated By
- BioGRID