FXYD7
Gene Ontology Biological Process
Gene Ontology Cellular Component
ATP1B1
Gene Ontology Biological Process
- blastocyst development [ISO]
- cardiac muscle contraction [ISO]
- cellular calcium ion homeostasis [ISO]
- cellular potassium ion homeostasis [ISO]
- cellular sodium ion homeostasis [ISO]
- membrane repolarization [ISO]
- metal ion transport [IDA]
- positive regulation of ATP catabolic process [ISO]
- positive regulation of ATPase activity [ISO]
- positive regulation of calcium:sodium antiporter activity [ISO]
- positive regulation of potassium ion import [ISO]
- positive regulation of potassium ion transmembrane transporter activity [ISO]
- positive regulation of sodium ion export from cell [ISO]
- potassium ion import [ISO]
- potassium ion transport [IDA]
- protein localization to plasma membrane [ISO]
- protein stabilization [ISO]
- regulation of calcium ion transmembrane transport [ISO]
- regulation of cardiac muscle contraction by calcium ion signaling [ISO]
- regulation of gene expression [ISO]
- relaxation of cardiac muscle [ISO]
- response to hypoxia [IDA]
- sodium ion export from cell [ISO]
- sodium ion transmembrane transport [IDA]
- sodium ion transport [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
FXYD7 is a brain-specific regulator of Na,K-ATPase alpha 1-beta isozymes.
Recently, corticosteroid hormone-induced factor (CHIF) and the gamma-subunit, two members of the FXYD family of small proteins, have been identified as regulators of renal Na,K-ATPase. In this study, we have investigated the tissue distribution and the structural and functional properties of FXYD7, another family member which has not yet been characterized. Expressed exclusively in the brain, FXYD7 is a type ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID