NPY
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [TAS]
- adult feeding behavior [ISS]
- behavior [TAS]
- blood circulation [NAS]
- calcium ion transport [TAS]
- cell proliferation [TAS]
- cellular component movement [TAS]
- central nervous system neuron development [IEP]
- cerebral cortex development [IEP]
- digestion [NAS]
- feeding behavior [TAS]
- neuron projection development [IEP]
- neuropeptide signaling pathway [IBA]
- positive regulation of appetite [ISS]
- regulation of appetite [IBA]
- synaptic transmission [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
NPY1R
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Reconstituted Complex
An interaction is inferred between proteins in vitro. This can include proteins in recombinant form or proteins isolated directly from cells with recombinant or purified bait. For example, GST pull-down assays where a GST-tagged protein is first isolated and then used to fish interactors from cell lysates are considered reconstituted complexes (e.g. PUBMED: 14657240, Fig. 4A or PUBMED: 14761940, Fig. 5). This can also include gel-shifts, surface plasmon resonance, isothermal titration calorimetry (ITC) and bio-layer interferometry (BLI) experiments. The bait-hit directionality may not be clear for 2 interacting proteins. In these cases the directionality is up to the discretion of the curator.
Publication
Cloning and functional expression of a cDNA encoding a human type 2 neuropeptide Y receptor.
Neuropeptide Y (NPY) is a 36-amino acid polypeptide that is widely distributed in the central nervous system and periphery. Pharmacological studies have suggested that there are at least three receptor subtypes, Y1, Y2, and Y3. Cloning of the Y1 subtype has been reported previously. Here we report the isolation by expression cloning of a cDNA encoding a human NPY receptor ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID