PREY

MPDZ

AI225843, B930003D11Rik, MUPP1, RP23-59O12.1
multiple PDZ domain protein
GO Process (2)
GO Function (2)
GO Component (6)
Mus musculus

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm.

Vassilev A, Kaneko KJ, Shu H, Zhao Y, DePamphilis ML

Mammals express four highly conserved TEAD/TEF transcription factors that bind the same DNA sequence, but serve different functions during development. TEAD-2/TEF-4 protein purified from mouse cells was associated predominantly with a novel TEAD-binding domain at the amino terminus of YAP65, a powerful transcriptional coactivator. YAP65 interacted specifically with the carboxyl terminus of all four TEAD proteins. Both this interaction and ... [more]

Genes Dev. May. 15, 2001; 15(10);1229-41 [Pubmed: 11358867]

Throughput

  • Low Throughput

Curated By

  • BioGRID