RAB3B
Gene Ontology Biological Process
- GTP catabolic process [IBA, IDA]
- Rab protein signal transduction [IBA]
- antigen processing and presentation [IMP]
- intracellular protein transport [IBA]
- positive regulation of dopamine uptake involved in synaptic transmission [IDA]
- protein localization to plasma membrane [IBA]
- protein secretion [IBA]
- regulation of exocytosis [IBA]
- regulation of vesicle size [IDA]
- synaptic vesicle exocytosis [IBA]
- vesicle docking involved in exocytosis [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
GDI1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Reconstituted Complex
An interaction is inferred between proteins in vitro. This can include proteins in recombinant form or proteins isolated directly from cells with recombinant or purified bait. For example, GST pull-down assays where a GST-tagged protein is first isolated and then used to fish interactors from cell lysates are considered reconstituted complexes (e.g. PUBMED: 14657240, Fig. 4A or PUBMED: 14761940, Fig. 5). This can also include gel-shifts, surface plasmon resonance, isothermal titration calorimetry (ITC) and bio-layer interferometry (BLI) experiments. The bait-hit directionality may not be clear for 2 interacting proteins. In these cases the directionality is up to the discretion of the curator.
Publication
Rab3B in human platelet is membrane bound and interacts with Ca(2+)/calmodulin.
The subcellular distribution of Rab3B in fresh and aged platelets was determined and majority of the protein was localized with the particulate fraction with only a minor amount detected in the cytosol. Rab3B was pulled out from platelet particulate fraction with GST-RabGDI-alpha fusion protein. Using GST-Rab3B in in vitro pull-down experiments, the binding of calmodulin from platelet cytosol to Rab3B ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| GDI1 RAB3B | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.8182 | BioGRID | 3223269 |
Curated By
- BioGRID