BAIT
MIR107
MIRN107, miR-107
microRNA 107
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
P3H1
GROS1, LEPRE1, OI8, PSEC0109
prolyl 3-hydroxylase 1
GO Process (11)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
- bone development [IMP]
- chaperone-mediated protein folding [ISS]
- collagen metabolic process [ISS]
- extracellular matrix organization [TAS]
- negative regulation of cell proliferation [NAS]
- negative regulation of post-translational protein modification [IMP]
- peptidyl-proline hydroxylation [ISS]
- protein folding [IMP]
- protein hydroxylation [IMP]
- protein stabilization [IMP]
- regulation of protein secretion [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Protein-RNA
An interaction is detected between and protein and an RNA in vitro.
Publication
A Compendium of RNA-Binding Proteins that Regulate MicroRNA Biogenesis.
During microRNA (miRNA) biogenesis, two endonucleolytic reactions convert stem-loop-structured precursors into mature miRNAs. These processing steps can be posttranscriptionally regulated by RNA-binding proteins (RBPs). Here, we have used a proteomics-based pull-down approach to map and characterize the interactome of a multitude of pre-miRNAs. We identify ∼180 RBPs that interact specifically with distinct pre-miRNAs. For functional validation, we combined RNAi and CRISPR/Cas-mediated knockout ... [more]
Mol. Cell Apr. 20, 2017; 66(2);270-284.e13 [Pubmed: 28431233]
Throughput
- High Throughput
Curated By
- BioGRID