GRIN2B
Gene Ontology Biological Process
- action potential [IMP]
- associative learning [IMP]
- behavioral fear response [ISO]
- behavioral response to pain [ISO]
- calcium ion transmembrane transport [ISO]
- calcium ion transport [ISO]
- cation transmembrane transport [ISO]
- cation transport [ISO]
- cellular response to amino acid stimulus [IEP]
- cellular response to dsRNA [IEP]
- cellular response to growth factor stimulus [IEP]
- cellular response to lipid [IEP]
- cellular response to magnesium starvation [IEP]
- cellular response to manganese ion [IEP]
- cellular response to organic cyclic compound [IEP]
- cerebral cortex development [IEP]
- detection of mechanical stimulus involved in sensory perception of pain [ISO]
- fear response [ISO]
- hippocampus development [IEP]
- in utero embryonic development [ISO]
- ion transmembrane transport [IDA]
- ionotropic glutamate receptor signaling pathway [IDA, ISO]
- learning [ISO]
- learning or memory [TAS]
- long-term memory [IEP]
- memory [IDA, ISO]
- multicellular organismal response to stress [IEP]
- positive regulation of cell death [IDA, IMP]
- positive regulation of glutamate secretion [IDA]
- positive regulation of synaptic transmission [IMP]
- receptor clustering [IDA]
- regulation of MAPK cascade [IMP]
- regulation of excitatory postsynaptic membrane potential [ISO]
- regulation of long-term neuronal synaptic plasticity [IMP]
- regulation of postsynaptic membrane potential [ISO]
- regulation of protein kinase A signaling [ISO]
- regulation of synaptic plasticity [ISO]
- response to amine [IEP]
- response to amphetamine [IEP]
- response to calcium ion [IEP]
- response to carbohydrate [IEP]
- response to cocaine [IEP]
- response to cytokine [IEP]
- response to electrical stimulus [IEP]
- response to ethanol [IEP, ISO]
- response to fungicide [IEP]
- response to growth hormone [IEP]
- response to magnesium ion [IEP]
- response to manganese ion [IEP]
- response to mechanical stimulus [IEP]
- response to methylmercury [IEP]
- response to organic cyclic compound [IEP]
- response to other organism [IEP]
- response to toxic substance [IEP]
- rhythmic process [IDA]
- sensory organ development [ISO]
- startle response [ISO]
- suckling behavior [ISO]
- synaptic transmission [ISO]
- synaptic transmission, glutamatergic [IBA]
Gene Ontology Molecular Function- D2 dopamine receptor binding [IPI]
- N-methyl-D-aspartate selective glutamate receptor activity [IDA, ISO]
- beta-catenin binding [IPI]
- calcium channel activity [ISO]
- cation channel activity [ISO]
- cell adhesion molecule binding [IPI]
- drug binding [IPI]
- extracellular-glutamate-gated ion channel activity [IDA]
- glycine binding [ISO]
- interleukin-1 receptor binding [IPI]
- ionotropic glutamate receptor activity [IDA]
- ionotropic glutamate receptor binding [IPI]
- neurotransmitter binding [IDA]
- protein binding [IPI]
- protein heterodimerization activity [IDA]
- receptor binding [IPI]
- zinc ion binding [IDA]
- D2 dopamine receptor binding [IPI]
- N-methyl-D-aspartate selective glutamate receptor activity [IDA, ISO]
- beta-catenin binding [IPI]
- calcium channel activity [ISO]
- cation channel activity [ISO]
- cell adhesion molecule binding [IPI]
- drug binding [IPI]
- extracellular-glutamate-gated ion channel activity [IDA]
- glycine binding [ISO]
- interleukin-1 receptor binding [IPI]
- ionotropic glutamate receptor activity [IDA]
- ionotropic glutamate receptor binding [IPI]
- neurotransmitter binding [IDA]
- protein binding [IPI]
- protein heterodimerization activity [IDA]
- receptor binding [IPI]
- zinc ion binding [IDA]
Gene Ontology Cellular Component
- N-methyl-D-aspartate selective glutamate receptor complex [IDA, ISO]
- Z disc [IDA]
- cell surface [ISO]
- dendritic spine [IDA]
- membrane [ISO]
- neuron projection [IDA, ISO]
- neuronal postsynaptic density [ISO]
- postsynaptic density [IDA, ISO]
- postsynaptic membrane [IBA, ISO]
- presynaptic membrane [IDA, ISO]
- synapse [IDA, ISO, TAS]
- synaptic cleft [IDA]
- synaptic vesicle [ISO]
- terminal bouton [IDA]
HOMER1
Gene Ontology Biological Process
- G-protein coupled glutamate receptor signaling pathway [IDA]
- behavioral response to cocaine [ISO]
- chemical homeostasis within a tissue [ISO]
- circadian rhythm [IEP]
- positive regulation of calcium ion transport [ISO]
- protein localization to synapse [IDA]
- regulation of calcium ion import [ISO]
- regulation of cation channel activity [ISO]
- regulation of store-operated calcium entry [IBA, ISO]
- response to calcium ion [ISO]
- response to cocaine [IEP]
- response to nicotine [IEP]
- skeletal muscle contraction [ISO]
- skeletal muscle fiber development [ISO]
Gene Ontology Molecular Function- G-protein coupled glutamate receptor binding [IPI]
- identical protein binding [IPI]
- ion channel binding [ISO]
- protein binding [IPI]
- protein complex scaffold [IPI]
- protein heterodimerization activity [IPI]
- receptor binding [IDA]
- scaffold protein binding [IPI]
- type 5 metabotropic glutamate receptor binding [IPI]
- G-protein coupled glutamate receptor binding [IPI]
- identical protein binding [IPI]
- ion channel binding [ISO]
- protein binding [IPI]
- protein complex scaffold [IPI]
- protein heterodimerization activity [IPI]
- receptor binding [IDA]
- scaffold protein binding [IPI]
- type 5 metabotropic glutamate receptor binding [IPI]
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
NMDA di-heteromeric receptor populations and associated proteins in rat hippocampus.
Subunit composition of NMDA receptors (NMDARs) determines a range of physiological properties, downstream signaling effects, and binding partners. Differential localization of NR2A- or NR2B-containing NMDARs within the neuron and subunit-specific protein associations may explain differences in NR2A and NR2B contributions to synaptic plasticity and excitotoxic cell death. This question is complicated by the existence of tri-heteromeric complexes (NR1/NR2A/NR2B). To date, ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID