ITGB1
Gene Ontology Biological Process
- B cell differentiation [IC]
- axon guidance [TAS]
- blood coagulation [TAS]
- calcium-independent cell-matrix adhesion [IGI]
- cell junction assembly [TAS]
- cell migration [TAS]
- cell-cell adhesion mediated by integrin [IEP]
- cell-matrix adhesion [IMP]
- cell-substrate adhesion [IMP]
- cellular defense response [TAS]
- extracellular matrix organization [TAS]
- heterotypic cell-cell adhesion [IMP]
- homophilic cell adhesion via plasma membrane adhesion molecules [TAS]
- integrin-mediated signaling pathway [IMP]
- leukocyte cell-cell adhesion [IDA]
- leukocyte migration [TAS]
- leukocyte tethering or rolling [IMP]
- mesodermal cell differentiation [IEP]
- negative regulation of anoikis [IMP]
- positive regulation of apoptotic process [IGI]
- positive regulation of establishment of protein localization to plasma membrane [IDA]
- regulation of collagen catabolic process [IDA]
- regulation of immune response [TAS]
- stress fiber assembly [IMP]
- transforming growth factor beta receptor signaling pathway [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- cell surface [IDA]
- cytoplasm [IDA]
- extracellular vesicular exosome [IDA]
- filopodium [IDA]
- focal adhesion [IDA]
- integrin alpha1-beta1 complex [IDA]
- integrin alpha10-beta1 complex [IDA]
- integrin alpha11-beta1 complex [IDA]
- integrin alpha2-beta1 complex [IDA]
- integrin alpha3-beta1 complex [IDA]
- integrin alpha8-beta1 complex [TAS]
- integrin complex [NAS]
- invadopodium membrane [IDA]
- membrane [IDA]
- membrane raft [IDA]
- neuromuscular junction [IDA]
- plasma membrane [IDA, NAS, TAS]
- receptor complex [IDA]
- ruffle [TAS]
- ruffle membrane [IDA, NAS]
- sarcolemma [IDA]
ITGA8
Gene Ontology Biological Process
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Sequence and tissue distribution of the human integrin alpha 8 subunit: a beta 1-associated alpha subunit expressed in smooth muscle cells.
Integrins are a major family of cell adhesion molecules involved in cell-cell and cell-extracellular matrix interactions. Each integrin is a heterodimeric glycoprotein composed of an alpha and a beta subunit. We now report the cDNA sequence and distribution of a new human integrin alpha subunit. This sequence is 78% identical to the previously reported chicken alpha 8 integrin sequence. Thus, ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| ITGA8 ITGB1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9917 | BioGRID | 3055920 | |
| ITGA8 ITGB1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.5049 | BioGRID | 3275420 |
Curated By
- BioGRID