BAIT

GIT2

CAT-2, CAT2
G protein-coupled receptor kinase interacting ArfGAP 2
GO Process (1)
GO Function (1)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

PCLO

ACZ, tcag7.1085
piccolo presynaptic cytomatrix protein
Glioblastoma Project
Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

The GIT family of proteins forms multimers and associates with the presynaptic cytomatrix protein Piccolo.

Kim S, Ko J, Shin H, Lee JR, Lim C, Han JH, Altrock WD, Garner CC, Gundelfinger ED, Premont RT, Kaang BK, Kim E

The cytoskeletal matrix assembled at active zones (CAZ) is implicated in defining neurotransmitter release sites. However, little is known about the molecular mechanisms by which the CAZ is organized. Here we report a novel interaction between Piccolo, a core component of the CAZ, and GIT proteins, multidomain signaling integrators with GTPase-activating protein activity for ADP-ribosylation factor small GTPases. A small ... [more]

J. Biol. Chem. Feb. 21, 2003; 278(8);6291-300 [Pubmed: 12473661]

Throughput

  • Low Throughput

Curated By

  • BioGRID