BAIT
GIT2
CAT-2, CAT2
G protein-coupled receptor kinase interacting ArfGAP 2
GO Process (1)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
PCLO
ACZ, tcag7.1085
piccolo presynaptic cytomatrix protein
GO Process (2)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
The GIT family of proteins forms multimers and associates with the presynaptic cytomatrix protein Piccolo.
The cytoskeletal matrix assembled at active zones (CAZ) is implicated in defining neurotransmitter release sites. However, little is known about the molecular mechanisms by which the CAZ is organized. Here we report a novel interaction between Piccolo, a core component of the CAZ, and GIT proteins, multidomain signaling integrators with GTPase-activating protein activity for ADP-ribosylation factor small GTPases. A small ... [more]
J. Biol. Chem. Feb. 21, 2003; 278(8);6291-300 [Pubmed: 12473661]
Throughput
- Low Throughput
Curated By
- BioGRID