BAIT
CHRNA1
ACHRA, ACHRD, CHRNA, CMS2A, FCCMS, SCCMS
cholinergic receptor, nicotinic, alpha 1 (muscle)
GO Process (15)
GO Function (4)
GO Component (5)
Gene Ontology Biological Process
- cation transmembrane transport [IMP, ISS, TAS]
- ion transmembrane transport [TAS]
- muscle cell cellular homeostasis [IMP]
- musculoskeletal movement [IMP]
- neuromuscular junction development [IMP]
- neuromuscular process [IMP]
- neuromuscular synaptic transmission [IMP]
- neuron cellular homeostasis [IMP]
- neuronal action potential [IMP]
- regulation of membrane potential [IMP]
- signal transduction [TAS]
- skeletal muscle contraction [IMP]
- skeletal muscle tissue growth [IMP]
- synaptic transmission [TAS]
- transport [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
CHRND
ACHRD, CMS2A, FCCMS, SCCMS
cholinergic receptor, nicotinic, delta (muscle)
GO Process (8)
GO Function (0)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Intersubunit contacts governing assembly of the mammalian nicotinic acetylcholine receptor.
Through specific intersubunit contacts, the four subunits of the nicotinic acetylcholine receptor assemble into an alpha 2 beta gamma delta pentamer. The specificity of subunit association leads to formation of proper ligand binding sites and to transport of assembled pentamers to the cell surface. To identify determinants of subunit association, we constructed chimeric subunits, transfected them into HEK 293 cells, ... [more]
Neuron Mar. 01, 1995; 14(3);635-44 [Pubmed: 7695910]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| CHRND CHRNA1 | Reconstituted Complex Reconstituted Complex An interaction is detected between purified proteins in vitro. | Low | - | BioGRID | - |
Curated By
- BioGRID