BAIT
APOD
apolipoprotein D
GO Process (20)
GO Function (3)
GO Component (8)
Gene Ontology Biological Process
- aging [NAS]
- angiogenesis [NAS]
- brain development [ISS]
- glucose metabolic process [IDA]
- lipid metabolic process [IDA]
- lipid transport [NAS]
- negative regulation of T cell migration [IDA]
- negative regulation of cytokine production involved in inflammatory response [IDA]
- negative regulation of focal adhesion assembly [IMP]
- negative regulation of lipoprotein lipid oxidation [IDA]
- negative regulation of monocyte chemotactic protein-1 production [IDA]
- negative regulation of platelet-derived growth factor receptor signaling pathway [IDA]
- negative regulation of protein import into nucleus [IDA]
- negative regulation of smooth muscle cell proliferation [IDA]
- negative regulation of smooth muscle cell-matrix adhesion [IMP]
- peripheral nervous system axon regeneration [ISS]
- response to axon injury [ISS]
- response to drug [ISS]
- response to reactive oxygen species [IDA]
- tissue regeneration [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
APOA2
Apo-AII, ApoA-II, apoAII
apolipoprotein A-II
GO Process (34)
GO Function (13)
GO Component (10)
Gene Ontology Biological Process
- cellular lipid metabolic process [TAS]
- cholesterol efflux [IDA]
- cholesterol homeostasis [IDA]
- diacylglycerol catabolic process [IDA]
- high-density lipoprotein particle assembly [IDA]
- high-density lipoprotein particle clearance [IDA]
- high-density lipoprotein particle remodeling [IDA]
- lipoprotein metabolic process [TAS]
- low-density lipoprotein particle remodeling [IDA]
- negative regulation of cholesterol import [IDA]
- negative regulation of cholesterol transport [IMP]
- negative regulation of cholesterol transporter activity [IDA]
- negative regulation of cytokine secretion involved in immune response [IDA]
- negative regulation of lipase activity [IDA]
- negative regulation of lipid catabolic process [IDA]
- negative regulation of very-low-density lipoprotein particle remodeling [IDA]
- peptidyl-methionine modification [IDA]
- phosphatidylcholine biosynthetic process [IDA]
- phospholipid catabolic process [IDA]
- phospholipid efflux [IDA]
- phototransduction, visible light [TAS]
- positive regulation of catalytic activity [IDA]
- positive regulation of cholesterol esterification [IDA]
- positive regulation of interleukin-8 biosynthetic process [IDA]
- positive regulation of lipid catabolic process [IDA]
- protein folding [IDA]
- protein oxidation [IDA]
- regulation of protein stability [IDA]
- response to glucose [IDA]
- retinoid metabolic process [TAS]
- reverse cholesterol transport [IDA]
- small molecule metabolic process [TAS]
- triglyceride metabolic process [TAS]
- triglyceride-rich lipoprotein particle remodeling [IDA]
Gene Ontology Molecular Function- apolipoprotein receptor binding [IPI]
- cholesterol binding [IDA]
- cholesterol transporter activity [IDA]
- high-density lipoprotein particle receptor binding [IPI]
- lipase inhibitor activity [IDA]
- lipid binding [IDA]
- lipid transporter activity [IDA]
- phosphatidylcholine binding [IDA]
- phosphatidylcholine-sterol O-acyltransferase activator activity [IDA]
- phospholipid binding [IDA]
- protein binding [IPI]
- protein heterodimerization activity [IPI]
- protein homodimerization activity [IDA]
- apolipoprotein receptor binding [IPI]
- cholesterol binding [IDA]
- cholesterol transporter activity [IDA]
- high-density lipoprotein particle receptor binding [IPI]
- lipase inhibitor activity [IDA]
- lipid binding [IDA]
- lipid transporter activity [IDA]
- phosphatidylcholine binding [IDA]
- phosphatidylcholine-sterol O-acyltransferase activator activity [IDA]
- phospholipid binding [IDA]
- protein binding [IPI]
- protein heterodimerization activity [IPI]
- protein homodimerization activity [IDA]
Gene Ontology Cellular Component
- blood microparticle [IDA]
- chylomicron [IDA]
- cytosol [TAS]
- early endosome [TAS]
- endoplasmic reticulum lumen [TAS]
- extracellular region [NAS, TAS]
- extracellular vesicular exosome [IDA]
- high-density lipoprotein particle [IDA]
- spherical high-density lipoprotein particle [IDA]
- very-low-density lipoprotein particle [IDA]
Homo sapiens
Co-purification
An interaction is inferred from the identification of two or more protein subunits in a purified protein complex, as obtained by classical biochemical fractionation or affinity purification and one or more additional fractionation steps.
Publication
Structure of human apolipoprotein D: locations of the intermolecular and intramolecular disulfide links.
We have determined the primary structure of human apolipoprotein D (apoD) by aligning peptides derived from digestions by cyanogen bromide, trypsin, and chymotrypsin. Our results confirm the primary structure derived from cDNA [Drayna et al. (1986) J. Biol. Chem. 261, 16535-16539]. ApoD consists of 169 amino acid residues, including 5 cysteines. Tryptic peptide analysis indicated that Cys41 and Cys16 are ... [more]
Biochemistry Oct. 18, 1994; 33(41);12451-5 [Pubmed: 7918467]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| APOA2 APOD | Co-purification Co-purification An interaction is inferred from the identification of two or more protein subunits in a purified protein complex, as obtained by classical biochemical fractionation or affinity purification and one or more additional fractionation steps. | Low | - | BioGRID | 853069 |
Curated By
- BioGRID