FRET

An interaction is inferred when close proximity of interaction partners is detected by fluorescence resonance energy transfer between pairs of fluorophore-labeled molecules, such as occurs between CFP (donor) and YFP (acceptor) fusion proteins.

Publication

Subunit composition of mammalian transient receptor potential channels in living cells.

Hofmann T, Schaefer M, Schultz G, Gudermann T

Hormones, neurotransmitters, and growth factors give rise to calcium entry via receptor-activated cation channels that are activated downstream of phospholipase C activity. Members of the transient receptor potential channel (TRPC) family have been characterized as molecular substrates mediating receptor-activated cation influx. TRPC channels are assumed to be composed of multiple TRPC proteins. However, the cellular principles governing the assembly of ... [more]

Proc. Natl. Acad. Sci. U.S.A. May. 28, 2002; 99(11);7461-6 [Pubmed: 12032305]

Throughput

  • Low Throughput

Curated By

  • BioGRID