BAIT

CG14965

63BC-T3, Dmel\CG14965, ORF1, anon-63BC-T3, dmLD47616p, Dmel_CG14965
CG14965 gene product from transcript CG14965-RA
GO Process (0)
GO Function (0)
GO Component (0)
Drosophila melanogaster
PREY

HLH4C

CG3052, Dmel\CG3052, DroNHLH, EG:84H4.2, bHLH36, Dmel_CG3052
Helix loop helix protein 4C
GO Process (2)
GO Function (1)
GO Component (1)

Gene Ontology Cellular Component

Drosophila melanogaster

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

A Comprehensive Drosophila melanogaster Transcription Factor Interactome.

Shokri L, Inukai S, Hafner A, Weinand K, Hens K, Vedenko A, Gisselbrecht SS, Dainese R, Bischof J, Furger E, Feuz JD, Basler K, Deplancke B, Bulyk ML

Combinatorial interactions among transcription factors (TFs) play essential roles in generating gene expression specificity and diversity in metazoans. Using yeast 2-hybrid (Y2H) assays on nearly all sequence-specific Drosophila TFs, we identified 1,983 protein-protein interactions (PPIs), more than doubling the number of currently known PPIs among Drosophila TFs. For quality assessment, we validated a subset of our interactions using MITOMI and ... [more]

Cell Rep Dec. 16, 2018; 27(3);955-970.e7 [Pubmed: 30995488]

Throughput

  • High Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
CG14965 HLH4C
Two-hybrid
Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

High-BioGRID
-

Curated By

  • BioGRID