BAIT
REL
CG11992, Dmel\CG11992, NF-kappaB, NFkappaB, RELI, Rel-p110, Rel/NF-kappaB, ird, ird4, l(3)neo36, relish, Dmel_CG11992
Relish
GO Process (21)
GO Function (6)
GO Component (2)
Gene Ontology Biological Process
- Toll signaling pathway [TAS]
- cellular response to DNA damage stimulus [IMP]
- cellular response to amino acid starvation [IMP]
- defense response to Gram-negative bacterium [IGI, IMP, TAS]
- defense response to virus [IMP]
- dendrite morphogenesis [IMP]
- immune response [IEP, IMP, TAS]
- innate immune response [IDA, NAS]
- negative regulation of stem cell proliferation [IMP]
- peptidoglycan recognition protein signaling pathway [IMP]
- peripheral nervous system neuron development [IMP]
- positive regulation of antibacterial peptide biosynthetic process [IEP, IMP, NAS, TAS]
- positive regulation of antifungal peptide biosynthetic process [IMP]
- positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria [IMP]
- positive regulation of defense response to virus by host [IMP]
- positive regulation of gene expression [IMP]
- positive regulation of innate immune response [IMP]
- positive regulation of nitric oxide biosynthetic process [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA, TAS]
- response to bacterium [IDA, TAS]
- signal transduction [TAS]
Gene Ontology Molecular Function- DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- protein binding [IPI]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [IDA]
- sequence-specific DNA binding transcription factor activity [NAS, TAS]
- DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- protein binding [IPI]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [IDA]
- sequence-specific DNA binding transcription factor activity [NAS, TAS]
Drosophila melanogaster
PREY
CROC
CG5069, Dmel\CG5069, Dmfd1, FD1, FoxC, fd78E, Dmel_CG5069
crocodile
GO Process (6)
GO Function (5)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Drosophila melanogaster
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A Comprehensive Drosophila melanogaster Transcription Factor Interactome.
Combinatorial interactions among transcription factors (TFs) play essential roles in generating gene expression specificity and diversity in metazoans. Using yeast 2-hybrid (Y2H) assays on nearly all sequence-specific Drosophila TFs, we identified 1,983 protein-protein interactions (PPIs), more than doubling the number of currently known PPIs among Drosophila TFs. For quality assessment, we validated a subset of our interactions using MITOMI and ... [more]
Cell Rep Dec. 16, 2018; 27(3);955-970.e7 [Pubmed: 30995488]
Throughput
- High Throughput
Curated By
- BioGRID