BAIT
KCNC1
KV3.1, KV4, NGK2
potassium voltage-gated channel, Shaw-related subfamily, member 1
GO Process (3)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
KCNG3
KV10.1, KV6.3
potassium voltage-gated channel, subfamily G, member 3
GO Process (2)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Obligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome.
Voltage-gated K(+) channels control excitability in neuronal and various other tissues. We identified three unique alpha-subunits of voltage-gated K(+)-channels in the human genome. Analysis of the full-length sequences indicated that one represents a previously uncharacterized member of the Kv6 subfamily, Kv6.3, whereas the others are the first members of two unique subfamilies, Kv10.1 and Kv11.1. Although they have all of ... [more]
Proc. Natl. Acad. Sci. U.S.A. Jun. 11, 2002; 99(12);7986-91 [Pubmed: 12060745]
Throughput
- Low Throughput
Curated By
- BioGRID