BAIT
KCNC1
KV3.1, KV4, NGK2
potassium voltage-gated channel, Shaw-related subfamily, member 1
GO Process (3)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
KCNV2
KV11.1, Kv8.2, RCD3B
potassium channel, subfamily V, member 2
GO Process (2)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Obligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome.
Voltage-gated K(+) channels control excitability in neuronal and various other tissues. We identified three unique alpha-subunits of voltage-gated K(+)-channels in the human genome. Analysis of the full-length sequences indicated that one represents a previously uncharacterized member of the Kv6 subfamily, Kv6.3, whereas the others are the first members of two unique subfamilies, Kv10.1 and Kv11.1. Although they have all of ... [more]
Proc. Natl. Acad. Sci. U.S.A. Jun. 11, 2002; 99(12);7986-91 [Pubmed: 12060745]
Throughput
- Low Throughput
Curated By
- BioGRID