BAIT

PAQR9

progestin and adipoQ receptor family member IX
GO Process (0)
GO Function (1)
GO Component (0)

Gene Ontology Molecular Function

Homo sapiens
PREY

ESYT1

FAM62A, MBC2
extended synaptotagmin-like protein 1
GO Process (0)
GO Function (2)
GO Component (3)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

PAQR9 Modulates BAG6-mediated protein quality control of mislocalized membrane proteins.

You X, Lin Y, Hou Y, Xu L, Cao Q, Chen Y

Protein quality control is crucial for maintaining cellular homeostasis and its dysfunction is closely linked to human diseases. The post-translational protein quality control machinery mainly composed of BCL-2-associated athanogene 6 (BAG6) is responsible for triage of mislocalized membrane proteins (MLPs). However, it is unknown how the BAG6-mediated degradation of MLPs is regulated. We report here that PAQR9, a member of ... [more]

Biochem. J. Dec. 31, 2019; 477(2);477-489 [Pubmed: 31904842]

Throughput

  • High Throughput

Curated By

  • BioGRID