BAIT
PAQR9
progestin and adipoQ receptor family member IX
GO Process (0)
GO Function (1)
GO Component (0)
Gene Ontology Molecular Function
Homo sapiens
PREY
NPEPPS
AAP-S, MP100, PSA
aminopeptidase puromycin sensitive
GO Process (3)
GO Function (0)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
PAQR9 Modulates BAG6-mediated protein quality control of mislocalized membrane proteins.
Protein quality control is crucial for maintaining cellular homeostasis and its dysfunction is closely linked to human diseases. The post-translational protein quality control machinery mainly composed of BCL-2-associated athanogene 6 (BAG6) is responsible for triage of mislocalized membrane proteins (MLPs). However, it is unknown how the BAG6-mediated degradation of MLPs is regulated. We report here that PAQR9, a member of ... [more]
Biochem. J. Dec. 31, 2019; 477(2);477-489 [Pubmed: 31904842]
Throughput
- High Throughput
Curated By
- BioGRID