BAIT
TRIM6
RNF89
tripartite motif containing 6
GO Process (1)
GO Function (0)
GO Component (1)
Gene Ontology Biological Process
Homo sapiens
PREY
RAB1A
RAB1, YPT1
RAB1A, member RAS oncogene family
GO Process (19)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- ER to Golgi vesicle-mediated transport [IGI, IMP]
- GTP catabolic process [IDA]
- Golgi organization [IMP]
- Rab protein signal transduction [IBA]
- autophagic vacuole assembly [IMP]
- autophagy [IMP]
- cargo loading into COPII-coated vesicle [IMP]
- cell migration [IMP]
- cilium assembly [IMP]
- defense response to bacterium [IMP]
- endocytosis [IMP]
- growth hormone secretion [IMP]
- interleukin-8 secretion [IMP]
- intracellular protein transport [IBA]
- mitotic cell cycle [TAS]
- positive regulation of glycoprotein metabolic process [IGI]
- vesicle transport along microtubule [IMP]
- vesicle-mediated transport [TAS]
- virion assembly [IGI, IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
TRIM6 promotes colorectal cancer cells proliferation and response to thiostrepton by TIS21/FoxM1.
Tripartite motif-containing proteins (TRIM) play a crucial role in carcinogenesis. Little attention has been focused on the possible functions of TRIM6 on carcinogenesis.The expression levels of TRIM6 were assessed in colorectal cancer (CRC) samples. TRIM6 expression was knocked down in CRC cell lines, and subjected to Cell counting kit-8 (CCK-8), bromodeoxyuridine (BrdU) incorporation and cell cycle assays. Immunoprecipitation and proteomics ... [more]
J. Exp. Clin. Cancer Res. Jan. 28, 2020; 39(1);23 [Pubmed: 31992359]
Throughput
- High Throughput
Curated By
- BioGRID