Co-crystal Structure

Interaction directly demonstrated at the atomic level by X-ray crystallography. Also used for NMR or Electron Microscopy (EM) structures. If there is no obvious bait-hit directionality to the interaction involving 3 or more proteins, then the co-crystallized proteins should be listed as a complex.

Publication

Crystallographic structure and functional interpretation of the cytoplasmic domain of erythrocyte membrane band 3.

Zhang D, Kiyatkin A, Bolin JT, Low PS

The red blood cell membrane (RBCM) is a primary model for animal cell plasma membranes. One of its major organizing centers is the cytoplasmic domain of band 3 (cdb3), which links multiple proteins to the membrane. Included among its peripheral protein ligands are ankyrin (the major bridge to the spectrin-actin skeleton), protein 4. 1, protein 4.2, aldolase, glyceraldehyde-3-phosphate dehydrogenase, phosphofructokinase, ... [more]

Blood Nov. 01, 2000; 96(9);2925-33 [Pubmed: 11049968]

Throughput

  • Low Throughput

Curated By

  • BioGRID