BAIT
LEPR
Fa
leptin receptor
GO Process (17)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [IDA]
- angiogenesis [IMP]
- cellular response to organic substance [IEP]
- cholesterol metabolic process [ISO]
- eating behavior [IMP]
- female pregnancy [IEP]
- generation of precursor metabolites and energy [NAS]
- leptin-mediated signaling pathway [IDA]
- negative regulation of gluconeogenesis [ISO]
- negative regulation of hydrolase activity [ISO]
- ovulation from ovarian follicle [IEP]
- positive regulation of MAPK cascade [IDA]
- response to estrogen [IEP]
- response to hypoxia [IEP]
- response to leptin [IEP]
- response to nicotine [IEP]
- response to nutrient [IEP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
APOD
AOPDGN
apolipoprotein D
GO Process (18)
GO Function (1)
GO Component (9)
Gene Ontology Biological Process
- aging [IEP]
- brain development [IEP]
- glucose metabolic process [ISO, ISS]
- lipid metabolic process [ISO, ISS]
- negative regulation of T cell migration [ISO, ISS]
- negative regulation of cytokine production involved in inflammatory response [ISO, ISS]
- negative regulation of focal adhesion assembly [ISO, ISS]
- negative regulation of lipoprotein lipid oxidation [ISO, ISS]
- negative regulation of monocyte chemotactic protein-1 production [ISO, ISS]
- negative regulation of platelet-derived growth factor receptor signaling pathway [ISO, ISS]
- negative regulation of protein import into nucleus [ISO, ISS]
- negative regulation of smooth muscle cell proliferation [ISO, ISS]
- negative regulation of smooth muscle cell-matrix adhesion [ISO, ISS]
- peripheral nervous system axon regeneration [IEP]
- response to axon injury [IEP]
- response to drug [IEP]
- response to reactive oxygen species [ISO, ISS]
- tissue regeneration [IEP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Apolipoprotein D interacts with the long-form leptin receptor: a hypothalamic function in the control of energy homeostasis.
... [more]
FASEB J. May. 01, 2001; 15(7);1329-31 [Pubmed: 11344130]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| APOD LEPR | Reconstituted Complex Reconstituted Complex An interaction is detected between purified proteins in vitro. | Low | - | BioGRID | - | |
| LEPR APOD | Reconstituted Complex Reconstituted Complex An interaction is detected between purified proteins in vitro. | Low | - | BioGRID | - |
Curated By
- BioGRID