BAIT

NREP

C5orf13, D4S114, P311, PRO1873, PTZ17, SEZ17
neuronal regeneration related protein
GO Process (0)
GO Function (1)
GO Component (0)

Gene Ontology Molecular Function

Homo sapiens
PREY

GDI2

HEL-S-46e, RABGDIB, RP11-318E3.2
GDP dissociation inhibitor 2
GO Process (3)
GO Function (2)
GO Component (5)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Novel RNA-binding protein P311 binds eukaryotic translation initiation factor 3 subunit b (eIF3b) to promote translation of transforming growth factor ?1-3 (TGF-?1-3).

Yue MM, Lv K, Meredith SC, Martindale JL, Gorospe M, Schuger L

P311, a conserved 8-kDa intracellular protein expressed in brain, smooth muscle, regenerating tissues, and malignant glioblastomas, represents the first documented stimulator of TGF-?1-3 translation in vitro and in vivo. Here we initiated efforts to define the mechanism underlying P311 function. PONDR® (Predictor Of Naturally Disordered Regions) analysis suggested and CD confirmed that P311 is an intrinsically disordered protein, therefore requiring ... [more]

J. Biol. Chem. Dec. 05, 2014; 289(49);33971-83 [Pubmed: 25336651]

Throughput

  • Low Throughput

Curated By

  • BioGRID