An interaction is inferred from the identification of two or more protein subunits in a purified protein complex, as obtained by classical biochemical fractionation or affinity purification and one or more additional fractionation steps.

Publication

Purification and molecular cloning of a novel essential component of the apolipoprotein B mRNA editing enzyme-complex.

Lellek H, Kirsten R, Diehl I, Apostel F, Buck F, Greeve J

Editing of apolipoprotein B (apoB) mRNA requires the catalytic component APOBEC-1 together with "auxiliary" proteins that have not been conclusively characterized so far. Here we report the purification of these additional components of the apoB mRNA editing enzyme-complex from rat liver and the cDNA cloning of the novel APOBEC-1-stimulating protein (ASP). Two proteins copurified into the final active fraction and ... [more]

J. Biol. Chem. Jun. 30, 2000; 275(26);19848-56 [Pubmed: 10781591]

Throughput

Low Throughput

Curated By

BioGRID

Interaction Summary

A1CF

Gene Ontology Biological Process

Gene Ontology Molecular Function

RNA binding [TAS]double-stranded RNA binding [IDA]protein binding [IPI]single-stranded RNA binding [IDA]

Gene Ontology Cellular Component

KHSRP