BAIT
PLCG1
PPLCA
phospholipase C, gamma 1
GO Process (19)
GO Function (8)
GO Component (9)
Gene Ontology Biological Process
- T cell receptor signaling pathway [ISO]
- calcium ion transport [IMP]
- calcium-mediated signaling [ISO]
- cell migration [ISO]
- cellular response to epidermal growth factor stimulus [ISO, ISS]
- epidermal growth factor receptor signaling pathway [ISO]
- in utero embryonic development [ISO]
- inositol trisphosphate biosynthetic process [IMP]
- positive regulation of angiogenesis [ISO]
- positive regulation of blood vessel endothelial cell migration [ISO]
- positive regulation of epithelial cell migration [IMP, ISO]
- positive regulation of release of sequestered calcium ion into cytosol [ISO]
- protein secretion [IMP]
- regulation of store-operated calcium channel activity [IMP]
- response to gravity [IEP]
- response to hydrogen peroxide [IEP]
- response to morphine [IEP]
- response to organonitrogen compound [IEP]
- signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
MAP6
2810411E12Rik, Map-6, Mtap6, STOP
microtubule-associated protein 6
GO Process (2)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Microtubule-associated protein 6 mediates neuronal connectivity through Semaphorin 3E-dependent signalling for axonal growth.
Structural microtubule associated proteins (MAPs) stabilize microtubules, a property that was thought to be essential for development, maintenance and function of neuronal circuits. However, deletion of the structural MAPs in mice does not lead to major neurodevelopment defects. Here we demonstrate a role for MAP6 in brain wiring that is independent of microtubule binding. We find that MAP6 deletion disrupts ... [more]
Nat Commun Jun. 03, 2015; 6();7246 [Pubmed: 26037503]
Throughput
- Low Throughput
Curated By
- BioGRID