SNTA1
Gene Ontology Biological Process
- negative regulation of peptidyl-cysteine S-nitrosylation [ISO]
- neuromuscular junction development [ISO]
- regulation of heart rate [ISO]
- regulation of sodium ion transmembrane transport [ISO]
- regulation of vasoconstriction by circulating norepinephrine [ISO]
- regulation of ventricular cardiac muscle cell membrane repolarization [ISO]
- ventricular cardiac muscle cell action potential [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
AQP4
Gene Ontology Biological Process
- carbon dioxide transport [IDA]
- cellular response to estradiol stimulus [IEP]
- cellular response to glucose stimulus [IMP]
- cellular response to interferon-gamma [ISO]
- cellular response to interleukin-1 [IEP]
- cellular response to interleukin-6 [IEP]
- cellular water homeostasis [IBA]
- female pregnancy [IEP]
- glycerol transport [IBA]
- hyperosmotic salinity response [IEP]
- ion transmembrane transport [IBA]
- multicellular organismal water homeostasis [ISO]
- negative regulation of cell adhesion molecule production [IMP]
- negative regulation of interleukin-1 beta production [IMP]
- negative regulation of interleukin-6 production [IMP]
- protein homooligomerization [IDA]
- regulation of vascular endothelial growth factor production [IMP]
- renal water absorption [ISO]
- response to glucocorticoid [IEP]
- response to radiation [IEP]
- sensory perception of sound [ISO]
- transmembrane transport [ISO]
- water homeostasis [ISO]
- water transport [IDA, ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- T-tubule [IDA]
- basal plasma membrane [IDA]
- basolateral plasma membrane [IDA, ISO]
- cell projection membrane [IDA]
- cell-cell junction [ISO]
- cytoplasm [ISO]
- external side of plasma membrane [ISO]
- integral component of plasma membrane [IDA]
- membrane [IDA]
- plasma membrane [ISO]
- protein complex [IDA]
- sarcolemma [IDA]
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Syntrophin-dependent expression and localization of Aquaporin-4 water channel protein.
The Aquaporin-4 (AQP4) water channel contributes to brain water homeostasis in perivascular astrocyte endfeet where it is concentrated. We postulated that AQP4 is tethered at this site by binding of the AQP4 C terminus to the PSD95-Discs large-ZO1 (PDZ) domain of syntrophin, a component of the dystrophin protein complex. Chemical cross-linking and coimmunoprecipitations from brain demonstrated AQP4 in association with ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID