BAIT

LRP2

DBS, GP330
low density lipoprotein receptor-related protein 2
Homo sapiens
PREY

ANKS1B

AIDA, AIDA-1, ANKS2, EB-1, EB1, cajalin-2
ankyrin repeat and sterile alpha motif domain containing 1B
GO Process (0)
GO Function (1)
GO Component (0)

Gene Ontology Molecular Function

Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Functional interaction of megalin with the megalinbinding protein (MegBP), a novel tetratrico peptide repeat-containing adaptor molecule.

Petersen HH, Hilpert J, Militz D, Zandler V, Jacobsen C, Roebroek AJ, Willnow TE

Megalin is a member of the LDL receptor gene family that plays an important role in forebrain development and in cellular vitamin D metabolism through endocytic uptake of vitamin D metabolites. Similar to other receptors in this gene family, megalin is believed to functionally interact with intracellular proteins through adaptors that bind to the receptor tail and regulate its endocytic ... [more]

J. Cell. Sci. Feb. 01, 2003; 116(0);453-61 [Pubmed: 12508107]

Throughput

  • Low Throughput

Curated By

  • BioGRID