BAIT
DAPK3
ZIPK, dlk
death-associated protein kinase 3
GO Process (17)
GO Function (9)
GO Component (3)
Gene Ontology Biological Process
- apoptotic process [ISO]
- apoptotic signaling pathway [IDA, IGI]
- cellular response to interferon-gamma [IMP, ISO]
- intracellular signal transduction [IDA, ISO]
- negative regulation of translation [ISO]
- positive regulation of apoptotic process [ISO]
- positive regulation of canonical Wnt signaling pathway [ISO]
- positive regulation of cell migration [IMP]
- positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [ISO]
- protein autophosphorylation [ISO]
- protein phosphorylation [IBA, IDA, ISO]
- regulation of actin cytoskeleton reorganization [ISO]
- regulation of apoptotic process [IBA]
- regulation of cell shape [IMP]
- regulation of focal adhesion assembly [ISO]
- regulation of mitotic cell cycle [ISO]
- regulation of myosin II filament organization [IMP]
Gene Ontology Molecular Function
Mus musculus
PREY
DAPK3
ZIPK, dlk
death-associated protein kinase 3
GO Process (17)
GO Function (9)
GO Component (3)
Gene Ontology Biological Process
- apoptotic process [ISO]
- apoptotic signaling pathway [IDA, IGI]
- cellular response to interferon-gamma [IMP, ISO]
- intracellular signal transduction [IDA, ISO]
- negative regulation of translation [ISO]
- positive regulation of apoptotic process [ISO]
- positive regulation of canonical Wnt signaling pathway [ISO]
- positive regulation of cell migration [IMP]
- positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [ISO]
- protein autophosphorylation [ISO]
- protein phosphorylation [IBA, IDA, ISO]
- regulation of actin cytoskeleton reorganization [ISO]
- regulation of apoptotic process [IBA]
- regulation of cell shape [IMP]
- regulation of focal adhesion assembly [ISO]
- regulation of mitotic cell cycle [ISO]
- regulation of myosin II filament organization [IMP]
Gene Ontology Molecular Function
Mus musculus
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
ZIP kinase, a novel serine/threonine kinase which mediates apoptosis.
We have identified a novel serine/threonine kinase, designated ZIP kinase, which mediates apoptosis. ZIP kinase contains a leucine zipper structure at its C terminus, in addition to a kinase domain at its N terminus. ZIP kinase physically binds to ATF4, a member of the activating transcription factor/cyclic AMP-responsive element-binding protein (ATF/CREB) family, through interaction between their leucine zippers. The leucine ... [more]
Mol. Cell. Biol. Mar. 01, 1998; 18(3);1642-51 [Pubmed: 9488481]
Throughput
- Low Throughput
Curated By
- BioGRID