BAIT
ABCD1
ABC42, ALD, ALDP, AMN
ATP-binding cassette, sub-family D (ALD), member 1
GO Process (14)
GO Function (9)
GO Component (7)
Gene Ontology Biological Process
- ATP catabolic process [IDA]
- alpha-linolenic acid metabolic process [TAS]
- cellular lipid metabolic process [TAS]
- fatty acid beta-oxidation [IDA, IGI]
- fatty acid beta-oxidation using acyl-CoA oxidase [TAS]
- linoleic acid metabolic process [TAS]
- long-chain fatty acid catabolic process [IGI]
- peroxisomal long-chain fatty acid import [IGI]
- peroxisomal membrane transport [NAS]
- peroxisome organization [IDA, NAS]
- small molecule metabolic process [TAS]
- transmembrane transport [TAS]
- unsaturated fatty acid metabolic process [TAS]
- very long-chain fatty acid catabolic process [IDA, IGI]
Gene Ontology Molecular Function- ATP binding [IDA]
- ATPase activity [IDA]
- ATPase activity, coupled to transmembrane movement of substances [NAS]
- enzyme binding [IPI]
- identical protein binding [IPI]
- peroxisomal fatty-acyl-CoA transporter activity [IGI, TAS]
- protein binding [IPI]
- protein homodimerization activity [IDA]
- transporter activity [NAS]
- ATP binding [IDA]
- ATPase activity [IDA]
- ATPase activity, coupled to transmembrane movement of substances [NAS]
- enzyme binding [IPI]
- identical protein binding [IPI]
- peroxisomal fatty-acyl-CoA transporter activity [IGI, TAS]
- protein binding [IPI]
- protein homodimerization activity [IDA]
- transporter activity [NAS]
Gene Ontology Cellular Component
Homo sapiens
PREY
HNRNPAB
ABBP1, HNRPAB
heterogeneous nuclear ribonucleoprotein A/B
GO Process (2)
GO Function (5)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei.
Cells organize their actions partly through tightly controlled protein-protein interactions-collectively termed the interactome. Here we use crosslinking mass spectrometry (XL-MS) to chart the protein-protein interactions in intact human nuclei. Overall, we identified ∼8,700 crosslinks, of which 2/3 represent links connecting distinct proteins. From these data, we gain insights on interactions involving histone proteins. We observed that core histones on the ... [more]
Mol. Cell Proteomics Dec. 01, 2017; 17(10);2018-2033 [Pubmed: 30021884]
Throughput
- High Throughput
Additional Notes
- interaction identified using XL-MS (cross-linking mass spectrometry): unfractionated cells or TX100-insoluble fractions from cells were treated with cross-linker and cross-linked proteins were identified by mass-spectrometry; interaction is undirectional; therefore bait and prey/hit have been assigned arbitrarily; interactions with FDRs (false discovery rates) of 1% or less were reported; this interaction was not detected in a parallel experiment using TX100-soluble fractions
Curated By
- BioGRID