BAIT
PPP1R9B
Neb2
protein phosphatase 1, regulatory subunit 9B
GO Process (9)
GO Function (1)
GO Component (8)
Gene Ontology Biological Process
- actin filament organization [ISO]
- calcium-mediated signaling [ISO]
- cell migration [ISO, ISS]
- cellular response to morphine [ISO, ISS]
- dendrite development [ISO]
- filopodium assembly [ISO, ISS]
- negative regulation of cell growth [ISO]
- regulation of opioid receptor signaling pathway [ISO, ISS]
- regulation of protein phosphorylation [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
ACTR3
1200003A09Rik, Arp3
ARP3 actin-related protein 3
GO Process (14)
GO Function (3)
GO Component (14)
Gene Ontology Biological Process
- Arp2/3 complex-mediated actin nucleation [ISO]
- asymmetric cell division [IGI]
- cilium morphogenesis [ISO]
- establishment or maintenance of cell polarity [IGI]
- meiotic cell cycle [IGI]
- meiotic chromosome movement towards spindle pole [IGI]
- meiotic cytokinesis [IGI]
- positive regulation of actin filament polymerization [ISO]
- positive regulation of dendrite morphogenesis [ISO]
- positive regulation of filopodium assembly [ISO]
- positive regulation of lamellipodium assembly [ISO]
- positive regulation of neuron differentiation [ISO]
- regulation of myosin II filament organization [ISO]
- spindle localization [IGI]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The identification of a second actin-binding region in spinophilin/neurabin II.
Spinophilin/neurabin II is an actin-associated scaffolding protein enriched in the dendritic spines of neurons. Previously, the actin-binding domain (ABD) of spinophilin was localized to a domain between amino acids (aa) 1 and 154. In a mass spectrometry screen for spinophilin-binding proteins, we have identified an additional actin-binding region between aa 151 and 282. F-actin co-sedimentation and GST affinity chromotography experiments ... [more]
Brain Res. Mol. Brain Res. May. 19, 2004; 124(2);105-13 [Pubmed: 15135218]
Throughput
- Low Throughput
Curated By
- BioGRID