CD36
Gene Ontology Biological Process
- MyD88-dependent toll-like receptor signaling pathway [TAS]
- antigen processing and presentation of exogenous peptide antigen via MHC class I [TAS]
- antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [TAS]
- antigen processing and presentation of peptide antigen via MHC class I [TAS]
- blood coagulation [TAS]
- cGMP-mediated signaling [IDA]
- cellular lipid metabolic process [TAS]
- cholesterol transport [ISS]
- innate immune response [TAS]
- lipid metabolic process [NAS]
- lipid storage [IMP]
- lipoprotein transport [IMP, TAS]
- long-chain fatty acid import [IDA]
- low-density lipoprotein particle clearance [IMP]
- nitric oxide mediated signal transduction [IDA]
- plasma lipoprotein particle clearance [ISS]
- plasma membrane long-chain fatty acid transport [IDA]
- platelet activation [TAS]
- platelet degranulation [TAS]
- positive regulation of cell-matrix adhesion [IDA]
- positive regulation of macrophage derived foam cell differentiation [IMP]
- small molecule metabolic process [TAS]
- toll-like receptor 2 signaling pathway [TAS]
- toll-like receptor 4 signaling pathway [TAS]
- toll-like receptor TLR1:TLR2 signaling pathway [TAS]
- toll-like receptor TLR6:TLR2 signaling pathway [TAS]
- toll-like receptor signaling pathway [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
YES1
Gene Ontology Biological Process
- Fc-gamma receptor signaling pathway involved in phagocytosis [TAS]
- T cell costimulation [TAS]
- blood coagulation [TAS]
- cell differentiation [IBA]
- cellular protein modification process [TAS]
- cellular response to peptide hormone stimulus [IBA]
- innate immune response [IBA, TAS]
- leukocyte migration [TAS]
- peptidyl-tyrosine autophosphorylation [IBA]
- regulation of cell proliferation [IBA]
- regulation of vascular permeability [TAS]
- transmembrane receptor protein tyrosine kinase signaling pathway [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Membrane glycoprotein IV (CD36) is physically associated with the Fyn, Lyn, and Yes protein-tyrosine kinases in human platelets.
Activation of platelets with thrombin and other agonists causes a rapid increase in the phosphorylation of multiple proteins on tyrosine. To identify candidate protein-tyrosine kinases (PTKs; EC 2.7.1.112) that may be responsible for these phosphorylation events, we analyzed the expression of seven Src-family PTKs and examined the association of these kinases with known platelet membrane glycoproteins. Five Src-related PTKs were ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID