BAIT

E2F3

E2F-3, RP1-177P22.2
E2F transcription factor 3
Cell Cycle - Senescence Project
Human Papilloma Virus (HPV) Project
GO Process (3)
GO Function (2)
GO Component (5)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

RNF144A

RNF144, UBCE7IP4
ring finger protein 144A
UPS Project
GO Process (0)
GO Function (0)
GO Component (1)

Gene Ontology Cellular Component

Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Interaction of YY1 with E2Fs, mediated by RYBP, provides a mechanism for specificity of E2F function.

Schlisio S, Halperin T, Vidal M, Nevins JR

To explore mechanisms for specificity of function within the family of E2F transcription factors, we have identified proteins that interact with individual E2F proteins. A two-hybrid screen identified RYBP (Ring1- and YY1-binding protein) as a protein that interacts specifically with the E2F2 and E2F3 family members, dependent on the marked box domain in these proteins. The Cdc6 promoter contains adjacent ... [more]

EMBO J. Nov. 01, 2002; 21(21);5775-86 [Pubmed: 12411495]

Throughput

  • Low Throughput

Curated By

  • BioGRID