BAIT
CLIP2
CLIP, CLIP-115, CYLN2, WBSCR3, WBSCR4, WSCR3, WSCR4
CAP-GLY domain containing linker protein 2
GO Process (0)
GO Function (0)
GO Component (1)
Gene Ontology Cellular Component
Homo sapiens
PREY
CLASP2
cytoplasmic linker associated protein 2
GO Process (10)
GO Function (3)
GO Component (11)
Gene Ontology Biological Process
- axon guidance [TAS]
- establishment or maintenance of cell polarity [TAS]
- fucosylation [NAS]
- microtubule anchoring [IMP]
- microtubule nucleation [IMP]
- microtubule organizing center organization [IMP]
- mitotic cell cycle [TAS]
- negative regulation of microtubule depolymerization [NAS]
- regulation of microtubule polymerization or depolymerization [IMP]
- regulation of microtubule-based process [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts.
CLIP-170 and CLIP-115 are cytoplasmic linker proteins that associate specifically with the ends of growing microtubules and may act as anti-catastrophe factors. Here, we have isolated two CLIP-associated proteins (CLASPs), which are homologous to the Drosophila Orbit/Mast microtubule-associated protein. CLASPs bind CLIPs and microtubules, colocalize with the CLIPs at microtubule distal ends, and have microtubule-stabilizing effects in transfected cells. After ... [more]
Cell Mar. 23, 2001; 104(6);923-35 [Pubmed: 11290329]
Throughput
- Low Throughput
Additional Notes
- Figure 3C
Curated By
- BioGRID