BAIT

HDLBP

HBP, PRO2900, VGL
high density lipoprotein binding protein
GO Process (0)
GO Function (3)
GO Component (2)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

XPOT

XPO3
exportin, tRNA
GO Process (1)
GO Function (1)
GO Component (3)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

Export and transport of tRNA are coupled to a multi-protein complex.

Kruse C, Willkomm DK, Gruenweller A, Vollbrandt T, Sommer S, Busch S, Pfeiffer T, Brinkmann J, Hartmann RK, Mueller PK

Vigilin is a ubiquitous multi heterogeneous nuclear ribonucleoprotein (hnRNP) K homologous (KH)-domain protein. Here we demonstrate that purified recombinant human vigilin binds tRNA molecules with high affinity, although with limited specificity. Nuclear microinjection experiments revealed for the first time that the immuno-affinity-purified nuclear vigilin core complex (VCC(N)) as well as recombinant vigilin accelerate tRNA export from the nucleus in human ... [more]

Biochem. J. Feb. 15, 2000; 346(0);107-15 [Pubmed: 10657246]

Throughput

  • Low Throughput

Curated By

  • BioGRID