BAIT

CSE1L

CAS, CSE1, XPO2
CSE1 chromosome segregation 1-like (yeast)
GO Process (3)
GO Function (2)
GO Component (5)
Homo sapiens
PREY

KPNA2

IPOA1, QIP2, RCH1, SRP1alpha
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
Homo sapiens

Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

Evidence for distinct substrate specificities of importin alpha family members in nuclear protein import.

Koehler M, Speck C, Christiansen M, Bischoff FR, Prehn S, Haller H, Goerlich D, Hartmann E

Importin alpha plays a pivotal role in the classical nuclear protein import pathway. Importin alpha shuttles between nucleus and cytoplasm, binds nuclear localization signal-bearing proteins, and functions as an adapter to access the importin beta-dependent import pathway. In contrast to what is found for importin beta, several isoforms of importin alpha, which can be grouped into three subfamilies, exist in ... [more]

Mol. Cell. Biol. Nov. 01, 1999; 19(11);7782-91 [Pubmed: 10523667]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
KPNA2 CSE1L
Co-fractionation
Co-fractionation

Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.

High-BioGRID
3445390
KPNA2 CSE1L
Reconstituted Complex
Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Low-BioGRID
-

Curated By

  • BioGRID