SDCBP
Gene Ontology Biological Process
Gene Ontology Molecular Function- cell adhesion molecule binding [IPI]
- ephrin receptor binding [IPI]
- frizzled binding [ISO]
- glycoprotein binding [IPI]
- growth factor binding [IPI]
- identical protein binding [ISO]
- interleukin-5 receptor binding [ISO, ISS]
- neurexin family protein binding [IPI, NAS]
- protein C-terminus binding [IPI]
- protein N-terminus binding [ISO]
- protein binding [IPI]
- protein heterodimerization activity [IPI, ISO]
- protein homodimerization activity [IDA]
- syndecan binding [IPI, ISO]
- cell adhesion molecule binding [IPI]
- ephrin receptor binding [IPI]
- frizzled binding [ISO]
- glycoprotein binding [IPI]
- growth factor binding [IPI]
- identical protein binding [ISO]
- interleukin-5 receptor binding [ISO, ISS]
- neurexin family protein binding [IPI, NAS]
- protein C-terminus binding [IPI]
- protein N-terminus binding [ISO]
- protein binding [IPI]
- protein heterodimerization activity [IPI, ISO]
- protein homodimerization activity [IDA]
- syndecan binding [IPI, ISO]
Gene Ontology Cellular Component
SDCBP
Gene Ontology Biological Process
Gene Ontology Molecular Function- cell adhesion molecule binding [IPI]
- ephrin receptor binding [IPI]
- frizzled binding [ISO]
- glycoprotein binding [IPI]
- growth factor binding [IPI]
- identical protein binding [ISO]
- interleukin-5 receptor binding [ISO, ISS]
- neurexin family protein binding [IPI, NAS]
- protein C-terminus binding [IPI]
- protein N-terminus binding [ISO]
- protein binding [IPI]
- protein heterodimerization activity [IPI, ISO]
- protein homodimerization activity [IDA]
- syndecan binding [IPI, ISO]
- cell adhesion molecule binding [IPI]
- ephrin receptor binding [IPI]
- frizzled binding [ISO]
- glycoprotein binding [IPI]
- growth factor binding [IPI]
- identical protein binding [ISO]
- interleukin-5 receptor binding [ISO, ISS]
- neurexin family protein binding [IPI, NAS]
- protein C-terminus binding [IPI]
- protein N-terminus binding [ISO]
- protein binding [IPI]
- protein heterodimerization activity [IPI, ISO]
- protein homodimerization activity [IDA]
- syndecan binding [IPI, ISO]
Gene Ontology Cellular Component
Co-purification
An interaction is inferred from the identification of two or more protein subunits in a purified protein complex, as obtained by classical biochemical fractionation or affinity purification and one or more additional fractionation steps.
Publication
The neural cell recognition molecule neurofascin interacts with syntenin-1 but not with syntenin-2, both of which reveal self-associating activity.
Neurofascin belongs to the L1 subgroup of the immunoglobulin superfamily of cell adhesion molecules and is implicated in axonal growth and fasciculation. We used yeast two-hybrid screening to identify proteins that interact with neurofascin intracellularly and therefore might link it to trafficking, spatial targeting, or signaling pathways. Here, we demonstrate that rat syntenin-1, previously published as syntenin, mda-9, or TACIP18 ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| SDCBP SDCBP | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - | |
| SDCBP SDCBP | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | Low | - | BioGRID | - |
Curated By
- BioGRID