CAMK1
Gene Ontology Biological Process
- positive regulation of dendritic spine development [IMP]
- positive regulation of muscle cell differentiation [IMP]
- positive regulation of neuron projection development [IDA]
- positive regulation of protein serine/threonine kinase activity [IDA]
- positive regulation of synapse structural plasticity [IMP]
- protein phosphorylation [IDA]
- regulation of muscle cell differentiation [IDA]
- regulation of protein binding [IDA]
- regulation of protein localization [IDA]
Gene Ontology Molecular Function
CAMKK2
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Biochemical Activity (Phosphorylation)
An interaction is inferred from the biochemical effect of one protein upon another, for example, GTP-GDP exchange activity or phosphorylation of a substrate by a kinase. The bait protein executes the activity on the substrate hit protein. A Modification value is recorded for interactions of this type with the possible values Phosphorylation, Ubiquitination, Sumoylation, Dephosphorylation, Methylation, Prenylation, Acetylation, Deubiquitination, Proteolytic Processing, Glucosylation, Nedd(Rub1)ylation, Deacetylation, No Modification, Demethylation.
Publication
Inhibition of the Ca2+/calmodulin-dependent protein kinase I cascade by cAMP-dependent protein kinase.
Several recent studies have shown that Ca2+/calmodulin-dependent protein kinase I (CaMKI) is phosphorylated and activated by a protein kinase (CaMKK) that is itself subject to regulation by Ca2+/calmodulin. In the present study, we demonstrate that this enzyme cascade is regulated by cAMP-mediated activation of cAMP-dependent protein kinase (PKA). In vitro, CaMKK is phosphorylated by PKA and this is associated with ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID